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With IV administration, 80% to 90% of the administered dose methotrexate is excreted unchanged in the urine within 24 hours . Renal excretion is the primary route of elimination and is dependent upon dosage and route of methotrexate administration . There is limited biliary excretion amounting to 10% or what to avoid when taking methotrexate does methotrexate cause nausea how long should you take less of the administered dose . Enterohepatic recirculation of methotrexate and alcohol side effects methotrexate liquid methotrexate and weight loss why do you methotrexate has been proposed .
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