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Usage of clozaril:

clozaril CYP1A2 Inhibitors .
The CLOZARIL dose should clozaril be increased to the original dose when coadministration of strong CYP1A2 inhibitors is discontinued [see DOSAGE AND ADMINISTRATION, CLINICAL PHARMACOLOGY] . Reduce the CLOZARIL dose to one third of the clozaril original dose when CLOZARIL is coadministered with strong CYP1A2 inhibitors (e . , clozaril fluvoxamine, ciprofloxacin, or enoxacin) . Concomitant use of CLOZARIL and CYP1A2 inhibitors can increase plasma levels of clozapine, potentially resulting in adverse clozapine dispensing clozaril online clozaril controlled substance clozaril and seizures clozaril reactions .

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